FIGURE

Fig. 7

ID

ZDB-FIG-240621-83

Publication

Wang et al., 2024 - Muscone abrogates breast cancer progression through tumor angiogenic suppression via VEGF/PI3K/Akt/MAPK signaling pathways

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Fig. 7

Muscone suppresses tumor angiogenesis. A, B Immunofluorescence (IF) images of tumor stained for CD31, αSMA, collagen IV (Col4), lectin, and hypoxyprobe in MDA-MB-231 xenograft tumors; Scale bar of CD31, αSMA, collagen IV (Col4) and lectin, 100 µm, scale bar of hypoxyprobe, 500 µm. Branching index, pericyte coverage, basement membrane coverage, lectin perfusion and hypoxic areas were recorded via Fiji, and quantitative data are provided as mean ± SEM. C–F IF pictures of VEGFA and PDGFB in MDA-MB-231 xenograft tumors; Scale bar, 100 μm. Representative staining images and quantification. Data provided as mean ± SEM. n = 5 mice per cohort. *P < 0.05, **P < 0.01, and ***P < 0.001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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