FIGURE

Fig. 2

ID

ZDB-FIG-240621-78

Publication

Wang et al., 2024 - Muscone abrogates breast cancer progression through tumor angiogenic suppression via VEGF/PI3K/Akt/MAPK signaling pathways

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Fig. 2

Muscone suppresses TCM-induced HUVECs proliferation and migration in cellular models. A The muscone-based regulation of HUVECs viability, as assessed via CCK-8 assays. B, C Influence of TCM-exposed MDA-MB-231 and BT-549 cells pretreated with muscone on HUVECs viability, as detected via CCK-8 assays. D, E Scratch wound assay of HUVEC cells treated with TCM from tumor cells pretreated with muscone; Scale bar, 1000 µm. F, G The influence of TCM from cells pretreated with muscone on HUVECs cell migration, as detected via Transwell cell migration assays. Typical representation (F) and quantification of migrated HUVECs quantity (G). Scale bar: 1250 µm. Data is shown as mean ± SEM. n = 3. *P < 0.05, **P < 0.01, and ***P < 0.001 vs TCM from untreated cells

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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