FIGURE

Fig. 1

ID

ZDB-FIG-240515-1

Publication

Zaupa et al., 2024 - The Calmodulin-interacting peptide Pcp4a regulates feeding state-dependent behavioral choice in zebrafish

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Fig. 1

Feeding decreases abundance of Pcp4a (A) Heatmap with dendrogram of hierarchical clustering of proteins significantly (FDR < 0.05) differentially abundant in fed and not-fed 7 dpf wild-type larvae. Three biological replicas (pool of ten larvae each) were used for each feeding condition. (B) An enlarged detail from the heatmap in (A), showing Pcp4a reduced abundance in fed larvae. (C) Confocal images of the tectum of a 7 dpf elavl3:H2B-GCaMP6s larva, showing nuclei of neurons labeled with GCaMP6s and pcp4a’s mRNA localization. Scale bars, 50 μm. (D) Bar graph depicting fold change of pcp4a’s mRNA levels (in fed versus not-fed fish) in the brain of 7 dpf wild-type larvae. n = 6 for each condition. n indicates number of biological replicas (ten pooled brains per each replica). Statistical significance was determined with one-sample t test. Data are shown as mean ± standard error of the mean.

Expression Data

Genes:	GCaMP pcp4a
Fish:	jf5Tg/jf5Tg WT
Condition:	limited food availability
Anatomical Terms:	brain optic tectum nucleus
Stage:	Days 7-13

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	limited food availability
Observed In:	brain
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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