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Zaupa et al., 2024 - The Calmodulin-interacting peptide Pcp4a regulates feeding state-dependent behavioral choice in zebrafish
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Fig. 1 Feeding decreases abundance of Pcp4a (A) Heatmap with dendrogram of hierarchical clustering of proteins significantly (FDR < 0.05) differentially abundant in fed and not-fed 7 dpf wild-type larvae. Three biological replicas (pool of ten larvae each) were used for each feeding condition. (B) An enlarged detail from the heatmap in (A), showing Pcp4a reduced abundance in fed larvae. (C) Confocal images of the tectum of a 7 dpf elavl3:H2B-GCaMP6s larva, showing nuclei of neurons labeled with GCaMP6s and pcp4a’s mRNA localization. Scale bars, 50 μm. (D) Bar graph depicting fold change of pcp4a’s mRNA levels (in fed versus not-fed fish) in the brain of 7 dpf wild-type larvae. n = 6 for each condition. n indicates number of biological replicas (ten pooled brains per each replica). Statistical significance was determined with one-sample t test. Data are shown as mean ± standard error of the mean.

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neuron