FIGURE

Figure 3.

ID
ZDB-FIG-240405-56
Publication
Zhou et al., 2024 - Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia
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Figure 3.

VLZ administration enhances thrombogenesis in Tg (itga2b: eGFP) transgenic zebrafish.

(a) Timeline of the zebrafish intervention. (b) Toxicity effects of different doses of VLZ on fish survival and general development. (c) itga2b: eGFP thrombocytes in whole tail regions of control and VLZ (2.5, 5, and 10 μM) treated zebrafish. Bars represent 200 μm. (d) Quantification of itga2b: eGFP cells in each group (n=6 per group). (e) Flow cytometry analysis of GFP-labeled platelets of Tg (itga2b: eGFP) zebrafish embryos treated with different doses of VLZ. The data are shown as the mean ± SD. *p≤0.05, **p≤0.01, and ***p≤0.001, vs the control group.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
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