FIGURE

Figure 2

ID

ZDB-FIG-240315-89

Publication

Gao et al., 2024 - Embryonic Amoxicillin Exposure Has Limited Impact on Liver Development but Increases Susceptibility to NAFLD in Zebrafish Larvae

Other Figures

All Figure Page

Back to All Figure Page

Figure 2

Amoxicillin treatment has limited impact on zebrafish liver function. (A–D) Quantification of triglyceride, total cholesterol, ALT activity, and AST activity in 5 dpf larvae after amoxicillin treatment from 0.5 to 5 dpf. Three independent experiments. Mean + s.e.m. In ANOVA analysis, ns—not significant. (E) Representative Oil red O [3] staining of larvae at 7 dpf. Larvae were categorized as having none, mild, or severe hepatic steatosis. Arrows point to the liver area. (F) Quantification of hepatic steatosis by ORO staining in 7 dpf larvae after amoxicillin treatment. The numbers of larvae analyzed in each group are indicated. In Chi-square tests, ns—not significant. (G) WISH revealed the expression of cp and abcb11b at 7 dpf after amoxicillin treatment. Numbers indicate the ratio of representative staining observed. (H) H&E staining of liver tissues at 7 dpf after amoxicillin treatment from 0.5 to 5 dpf. Scale bars, (E) 50 µm, (G) 100 µm, (H) 5 µm. dpf, days post-fertilization; ALT, alanine aminotransferase; AST, aspartate aminotransferase.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.