FIGURE

Fig. 4

ID

ZDB-FIG-240205-26

Publication

Luckner et al., 2023 - Transcriptomic profiling of TLR-7-mediated immune-challenge in zebrafish embryos in the presence and absence of glucocorticoid-induced immunosuppression

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Results of the ORA on CP-responsive and IMQ-responsive DEGs on GO terms for biological processes. Gene ratio is defined as the ratio between the number of genes assigned to a specific term and the total number of genes assigned to at least one term during the analysis. Gene set enrichment is defined as the ratio between the number of genes assigned to a specific term and the size of the gene set defining this term. DEGs from the respective DGEAs were used as an input for each ORA. A: Selection of terms related to the immune-response or inflammation out of the 189 significantly overrepresented (padj. < 0.05, minimum 2 genes per terms) terms in response to CP. 3442 genes were assignable to at least one term. A list of all overrepresented GO terms on biological processes is provided in the supplementary information. B: All overrepresented terms on biological processes in response to IMQ. 141 genes were assignable to at least one term.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Conditions:	chemical treatment by environment: clobetasol propionate chemical treatment by environment: imiquimod
Observed In:	ammonium homeostasis biological process involved in interspecies interaction between organisms circadian regulation of gene expression defense response muscle contraction regulation of programmed cell death response to biotic stimulus response to other organism response to virus
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Ecotoxicol. Environ. Saf.