FIGURE

Fig 1

ID

ZDB-FIG-240202-8

Publication

Nielson et al., 2023 - Survival in macrophages induces enhanced virulence in Cryptococcus

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Fig 1

MECs show enhanced virulence in zebrafish larvae and mouse lungs. (A) Larvae inoculated with 20–70 fluorescent yeast prepared in one of three ways. Counts were performed by eye via live microscopy at 2 hpi and 1 through 4 days post-infection (dpi). Live counting allows for the assessment of yeast in expected and unexpected locations and focal planes. Charted are daily yeast counts normalized to counts at 2 hpi. Statistical comparisons represent the results of Mann-Whitney tests of log-transformed ratios. (B) Comparative fungal burden of TC-experienced (gray) and J774-experienced Cn in the lungs of mice infected intranasally with 1 × 10⁴ total CFU. Statistical comparisons represent unpaired t-tests of log-transformed ratios.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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