FIGURE

Fig 4

ID

ZDB-FIG-240105-67

Publication

Rothschild et al., 2023 - Constitutively active CaMKII Drives B lineage acute lymphoblastic leukemia/lymphoma in tp53 mutant zebrafish

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Fig 4

Lymphocytes are significantly expanded in the kidney marrow and spleen of rag2:EGFP-CA-CaMKII; tp53 mutant fish.

Lineage distributions as determined by cell morphology in the (A-D) kidney marrow and (E) spleen of 9–12 month old fish segregated into rag2:EGFP-CA-CaMKII on a wild type (black, n = 3), tp53 heterozygous (blue, n = 3), or tp53 mutant background (gray, n = 4). Cell populations were identified from eight to ten images of HEMA3 stained blood smears per fish. P values were calculated using one-way ANOVA followed by Tukey HSD. ** p<0.01. Scale bar is 10 μm in A.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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