FIGURE

Fig 8

ID

ZDB-FIG-231221-38

Publication

Flores et al., 2023 - Colonization of larval zebrafish (Danio rerio) with adherent-invasive Escherichia coli prevents recovery of the intestinal mucosa from drug-induced enterocolitis

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Fig 8

Deletion of fimH and ibeA in AIEC LF82 results in decreased tissue damage and neutrophil recruitment to the intestine compared to LF82. H&E longitudinal sections of the mid-intestine of larvae infected with (A) LF82 WT, (B) LF82ΔfimH, (C) LF82ΔfimH:fimH, (D) LF82ΔibeA, and (E) LF82ΔibeA:ibeA at 2 (i), 24 (ii), and 48 (iii) hpi. Representative images for n = 3. Scale bars = 50 µm. (F) Quantification of neutrophils per intestine for DSS-treated fish infected with abovementioned LF82 strains or paramecia-only control. Kruskal-Wallis test. n ≥11. *, P ≤ 0.05; **, P ≤ 0.001; ****P ≤ 0.0001; ns, not significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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