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FIGURE 7

ID

ZDB-FIG-231201-7

Publication

Guzelkaya et al., 2023 - A zebrafish model for studying the mechanisms of newborn hyperbilirubinemia and bilirubin-induced neurological damage

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FIGURE 7

Hyperbilirubinemia affects eye reflexes and swim behavior:(A) Turn of the eyes in response to light stimulation is displayed. Turn of the eye between t₀ and t₁ was measured as turn angle alpha. (B) Average turn angle of the eyes of larvae exposed to 3, 6, 9 and 15 µM doses of bilirubin is displayed. (C) Average swim distance of controls and larvae exposed to 9 µM bilirubin between 2 and 3 dpf at 4 and 6 dpf is displayed. Data are the mean ± SEM. (A″-C″) n = 20, 18, 22, 20, and 22 for control, 3, 6, 9, and 15 µM. (D) Directional swim behavior of the control and swirling swim behavior of the severely affected larvae are displayed.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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