brsk2ab−/− zebrafish showed a catch-up growth pattern. (A) Representative pictures of measured zebrafish. (B) The body lengths were measured at 2 dpf (WT: brsk2ab−/−, n = 120: 131), 3 dpf (n = 105: 105), 5 dpf (n = 100: 89), 2.5 mpf (n = 19: 21), and 4 mpf (n = 14: 16). The brsk2ab−/− larvae have shorter bodies than WT larvae at 2 dpf (WT vs. brsk2ab−/−, 3.760 ± 0.09 vs. 3.623 ± 0.09; p < 0.0001), 3 dpf (4.329 ± 0.14 vs. 4.170 ± 0.15; p < 0.0001), and 5 dpf (5.071 ± 0.21 vs. 4.819 ± 0.22; p < 0.0001), but there was no difference in body length at 2.5 mpf (21.19 ± 1.58 vs. 20.90 ± 2.31; p = 0.646) and 4 mpf (27.57 ± 1.66 vs. 28.04 ± 1.53; p = 0.425). Data are shown as mean ± SEM, **** p < 0.0001.
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