FIGURE

Fig. 5.

ID

ZDB-FIG-231116-144

Publication

Bañón et al., 2023 - Pioneer statoacoustic neurons guide neuroblast behaviour during otic ganglion assembly

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Fig. 5.

Pioneer SAG neurons of extra-otic origin initially populate the coalescence region. (A) Extra-otic pioneer SAG neurons are specified anterior to the otic placode (white dashed oval) and posterior to the trigeminal ganglion (magenta signal in left corner) at around 13 hpf. Pioneer SAG neurons migrate and initially populate the coalescence region in anterior locations of the otic placode. Migrating cells outlined in top and lower panels. Medial panels show different cell trajectories towards the otic vesicle (dashed line). (B) Pioneer SAG neurons are Neurod⁺ cells that do not ingress into the otic epithelium. Ingression takes place at 13.5 hpf (arrow) but not later (inhibitory symbol). Otic vesicle outlined with dashed line. Right panel shows ingressing cells in magenta and non-ingressing cells in green. (B′) Quantification of the number of cells ingressing or not depending on gene expression. Scale bars: 20 µm (A); 10 µm (B).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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