FIGURE

Fig. 3

ID
ZDB-FIG-231102-18
Publication
Zisi et al., 2022 - Small Molecule-mediated Disruption of Ribosome Biogenesis Synergizes With FGFR Inhibitors to Suppress Glioma Cell Growth
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Fig. 3

BMH-21 synergizes with TMZ (A) Cell viability of glioma cell lines compared with NHA upon 72 h treatment. (B) Indicated protein levels following 48 h treatment; beta-actin served as a loading control. (C–D) IF-based Quantification of Cleaved Cas3-positive nuclei in (C) serum- and (D) NSC-grown glioma lines (48 h). (E) Cell-cycle distribution barplot of A172 and U18 upon 24 h treatment. (F) Migration assay showing cell-migratory capacity during 6 h-treatment (G) Colony formation assay of H4 and U18 following 72 h-treatment and then 15-day-culture in drug-free media.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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