FIGURE

Figure 5.

ID

ZDB-FIG-231012-6

Publication

Oyarbide et al., 2023 - SBDS^R126T rescues survival of sbds^-/- zebrafish in a dose-dependent manner independently of Tp53

Other Figures

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Figure 5.

Incrosses of sbds KO with one copy of the transgene have severe malformations in early stages of development.

(A) Crosses between WT and sbds KO fish. (B) Embryos obtained from crosses at 24 and 48 hpf. (C) Percentage of deformed fish in the first 72 hpf. (D) qRT-PCR analysis of critical genes involved in ribosomes, metabolism, and tp53 pathways.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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