FIGURE

Fig. 7.

ID

ZDB-FIG-231002-110

Publication

Leid et al., 2023 - Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism

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Fig. 7.

RNA sequencing of control and cora^stl325 identifies derangements metabolic gene expression. (A) Principal component analysis (PCA) plot of pooled sequencing libraries generated from control and cora^stl325 embryos at 96 hpf. Each dot represents a pool of 100 embryonic hearts. (B) Bar graph of the top Gene Ontology (GO) pathways associated with genes differentially expressed between control and cora^stl325 hearts. (C) Heat map of metabolic genes significant with significantly reduced expressed in cora^stl325 hearts. (D) Graphical representation of the number of differentially expressed metabolic genes associated with the TCA cycle (left) and the electron transport chain (right). Made with BioRender.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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