FIGURE

Figure 1

ID

ZDB-FIG-230814-198

Publication

Suzuki et al., 2023 - Cooperative contributions of the klf1 and klf17 genes in zebrafish primitive erythropoiesis

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Figure 1

The klf1-klf17 double mutant exhibited impairment of primitive erythropoiesis. (A–D) Live embryos at 48 hpf. The red colour of blood-circulating erythroid cells (arrowheads) was faint in the klf1-klf17 mutant (klf1^-/-klf17^-/-) (D) compared to those in the wild-type (klf1^+/-klf17^+/+) (A), klf1 mutant (klf1^-/-klf17^+/-) (B) and klf17 mutant (klf1^+/+klf17^-/-) (C). (E–H) Detection of haemoglobin (arrowheads) at 48 hpf. Haemoglobin production was examined by o-dianisidine staining. Haemoglobin production in the yolk was reduced in the klf1-klf17 mutant (H) compared to the wild-type (E), klf1 mutant (F) and klf17 mutant (G). Genotyping was performed by genomic PCR using locus-specific primers. Scale bar, 200 μm (A, E).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	klf1^uy19/uy19 klf17^uy21/uy21 klf1^uy19/uy19; klf17^uy21/uy21
Observed In:	erythroblast
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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