FIGURE

Fig. 1

ID

ZDB-FIG-230718-32

Publication

Schäfer et al., 2023 - Dual Action of Eeyarestatin 24 on Sec-Dependent Protein Secretion and Bacterial DNA

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Fig. 1

Summary of B. subtilis transcriptomic stress profiling results. (A) Chemical structures of ES24 and NFT. The nitrofuran ring is highlighted in red. (B) Number of regulated transcripts per regulon. Sec components and proteases potentially indicating secretion stress are highlighted. NfrAB is a nitro/flavin reductase under transcriptional control of the Spx regulator and among the most strongly activated transcripts for both ES24 and NFT treatment. (C) Number of induced transcripts per functional category of the respective gene products. Functional categories were assigned according to function, regulation, interaction, and expression data available on http://subtiwiki.uni-goettingen.de/. Transcripts that showed a log₂-fold change of ≥3 (p < 0.05) were considered as differentially regulated.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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