FIGURE

Figure 7

ID

ZDB-FIG-230707-96

Publication

Yue et al., 2023 - VBP1 negatively regulates CHIP and selectively inhibits the activity of hypoxia-inducible factor (HIF)-1α but not HIF-2α

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Figure 7

VBP1 expression is associated with the overall survival of ccRCC patients.A, Kaplan-Meier survival curves revealed that patients with low levels of VBP1 (bottom 50%, TPM < 5.94633) had significantly lower overall survival in the ccRCC, n = 532. B, Patients with mutated VHL with low levels of VBP1 (TPM < 5.94633) had significantly lower overall survival in the ccRCC, n = 163. RNA-seq expression profiles of VBP1 gene and corresponding clinical information for ccRCC and ccRCC VHL mutant patients were obtained from TCGA database. All data were standard TPM data and the statistical analyses were performed using R software. ccRCC, clear cell renal carcinoma; OS, overall survival; VBP1, pVHL binding protein 1.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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