Figure 9.

New multivariate Granger causality analysis of motor-correlated hindbrain neurons revealed neurons in the locus of Mesencephalic Locomotor Region (MLR) on the side of the visual grading driving activity of neurons in the contralateral MLR and on both sides in the medulla.

The distributions of the tail angles for turns (tail angle α with 45 < |α| < 90 , gray, top left of A-C) and the distributions of the new MVGC link angles (blue, bottom left of A-C) indicate a bias when the visual grading stimulus was presented on the right towards the left across 3 hindbrain planes spaced by 10µm (A: plane 5, dorsal to B: plane 7, analyzed in Figure 8; C: plane 9, ventral to plane 7). Across these three planes, a group of strong driver neurons (middle and right panels of A-C) was found located on the right, in the locus of the MLR. This is to our knowledge the first evidence of recruitment of cells in the MLR locus during locomotion. As expected from anatomy (Carbo-Tano et al., 2022), right MLR neurons drive contralateral neurons in the left MLR and in the medulla where the reticular formation is located, both on the right and left sides.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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