FIGURE

Fig. 5

ID

ZDB-FIG-230317-8

Publication

Smith et al., 2021 - Lysosomes and the pathogenesis of merosin-deficient congenital muscular dystrophy

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Fig. 5

Mean overall Lamp1-RFP fluorescence intensity in muscle fibers. (A) There is an overall increase in Lamp1-RFP expression at 3 dpf (n = 10 fibers) and 5 dpf (n = 25 fibers) in caf mutants compared with WT siblings that is not significant at 3dpf (P = 0.4431) but it is significant at 5 dpf (P = 0.0026). (B) There is no overall difference in Lamp1-RFP expression in immobilized caf mutants compared with immobilized WT siblings (P = 0.3164, n = 36 fibers), nor in sap mutants compared with their WT siblings (P = 0.789, n = 14 fibers). Bars represent mean ± SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	lama2^{teg15a/teg15a}
Observed In:	myotome lysosome
Stage:	Day 5

Phenotype Detail

Acknowledgments

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