FIGURE

Fig. 9

ID

ZDB-FIG-230317-12

Publication

Smith et al., 2021 - Lysosomes and the pathogenesis of merosin-deficient congenital muscular dystrophy

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Fig. 9

Vps34-IN1 treatment does not significantly improve the swimming behavior and dystrophic phenotype of caf mutants. (A and B) There is a small magnitude, non-significant, increase in time spent moving and total distance traveled in caf mutants after treatment with 100 nM Vps34-IN1 (n = 96). (C) There is no change in average velocity in caf mutants after treatment with 100 nM Vps34-IN1 (n = 96). (D) Birefringence intensity measurements show no significant improvement to the dystrophic phenotype of caf mutants after Vps34-IN1 treatment (n = 16). ^****P < 0.0001. Bars represent mean ± SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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