FIGURE

Fig. 6

ID

ZDB-FIG-230214-10

Publication

Caja et al., 2021 - The protein kinase LKB1 promotes self-renewal and blocks invasiveness in glioblastoma

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Fig. 6

Transcriptomic analysis of GBM cells after LKB1 knock-down. (a) Venn diagram and list showing common downregulated genes between U3031MG and U3034MG cells with a LogFC < −0.5 and FDR < 0.05. (b) Graphical representation of downregulated genes from the top GO BP terms (number of genes per category is shown by circle diameter; fold-change in expression by color). (c) Gene Ontology enrichment for BP of the 47 common downregulated genes after LKB1 silencing. Adjusted p-value is color-coded. (d) Graphical representation of the log-FC of the indicated genes (siLKB1 pool vs. siC from the Ampliseq analysis) derived from triplicate samples of the two GBM cultures. BP, biological process; FC, fold change; FDR, false discovery rate; GBM, glioblastoma; LKB1, liver kinase B1

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell. Physiol.