FIGURE
Figure 5
- ID
- ZDB-FIG-230131-77
- Publication
- Bulleeraz et al., 2023 - Leukemia-associated truncation of granulocyte colony-stimulating factor receptor impacts granulopoiesis throughout the life-course
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Figure 5
Effect of G-CSFR truncation mutation on emergency hematopoiesis. Wild-type (wt/wt) and homozygous (mdu27/mdu27) mutant csf3r embryos, either uninjected or injected with mRNA encoding G-CSF (+ csf3a) were subjected to WISH with mpo during primitive (A–D) and early definitive (F–I) hematopoiesis, with representative images shown. Individual embryos were assessed for the number of mpo+ cells for primitive (E) and definitive (J) hematopoiesis, with mean and SEM shown in red and level of statistical significance indicated (***: p < 0.001, *: p < 0.05, ns: not significant; n=17-30). |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Anatomical Term: | |
| Stage Range: | 26+ somites to Day 5 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage Range: | 26+ somites to Day 5 |
Phenotype Detail
Acknowledgments
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