FIGURE

Fig. 6

ID

ZDB-FIG-230130-4

Publication

Tang Gundersen et al., 2021 - Repurposing chlorpromazine for anti-leukaemic therapy by nanoparticle encapsulation

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Fig. 6

PLGA-based nanoparticles rapidly associate with AML cells. MOLM-13 cells were incubated Nile Red-loaded nanoparticles at 2% v/v (A). After various times of incubation, cells were washed, and their fluorescence analysed with an Accuri C6 flow cytometer. The results are the average of median fluorescence, and standard deviation from a triplicate experiment. Non-linear regression curves were made using SigmaPlot, ver. 9.01, (Systat Software, Inc., San Jose, CA, USA). (B-K): Cells incubated with Nile Red-loaded nanoparticles were fixed in 2% buffered formaldehyde (in pH 7.4 PBS containing Hoechst 33342) and imaged with confocal microscopy. The scale bars in the confocal micrographs represent 15 �m. See Supplementary Figure S1 for gating strategy

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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