FIGURE
Fig 6
- ID
- ZDB-FIG-221216-45
- Publication
- Grzegorski et al., 2022 - Genetic duplication of tissue factor reveals subfunctionalization in venous and arterial hemostasis
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Fig 6
Loss of TFb protects against spontaneous thrombosis in at3-/- larvae but does not improve long term survival.
(A) Fibrin deposits were assessed at 5 dpf. Deficiency of TFa did not alter thrombosis scores while loss of TFb led to less deposition (B) When followed for >1 year, f3 genotype did not influence at3-/- survival; however, all aa/bb offspring were lost by 120 days, consistent with TF dependent lethality. Statistical significance by binomial proportion test: *** < 0.001. A* represents AA or Aa, B* represents BB or Bb. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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