FIGURE

Fig 5

ID

ZDB-FIG-221216-44

Publication

Grzegorski et al., 2022 - Genetic duplication of tissue factor reveals subfunctionalization in venous and arterial hemostasis

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Fig 5

Loss of FIXb impairs clot formation in f3a-null offspring.

(A) Loss of f9b does not influence induced venous occlusion in A*/bb but does decrease total frequency of occlusion in aa/B* larvae at 3 dpf. (B) Loss of f9b does not significantly affect clot formation in A*/bb offspring. In aa/B* larvae, loss of f9b leads to a significant impairment of occlusive clot formation. Statistical significance by Mann-Whitney U testing: ** < 0.01. A* represents AA or Aa, B* represents BB or Bb. (C) Summary of data in (A) and (B) with proposed relative ohnolog occlusive activity in the presence and absence of FIX, in arterial versus venous systems.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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