FIGURE

Fig. 6

ID

ZDB-FIG-221128-37

Publication

Le et al., 2021 - Differential expression and hypoxia-mediated regulation of the N-myc downstream regulated gene family

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Fig. 6

Analysis of ndrg1a expression in zebrafish embryos following 8 h of anoxia. Wholemount in situ hybridization analysis revealing the distribution of ndrg1a transcript in 24 hpf zebrafish embryo exposed to 8 h of anoxia (B–B″, C–C′, D–D′, F–F″, H, J) relative to normoxic (stage-matched controls) (A–A″, E–E″, G, I) imaged from a lateral view (A–D′), a dorsal view (E–F″) and cross-sectional (G–J) views through the otic vesicles (G,H) and the trunk (I,J). (A′–B″, E–F″ are magnified views of (A,B,E,F). The mild (C,C′) and severe (D,D′) transcriptional responses are included to compare with the moderate response (B–B″, F–F″). aa, aortic arch; cp, cranial placodes; cv, caudal vein; da, dorsal aorta; ep, epiphysis; hgc, hatching gland cells; io, ionocyte; llp, lateral line primordium; mcev, mid-cerebral vein; ov, otic vesicle; pcv, posterior cardinal vein; pmbc, primordial midbrain channel; pd, pronephric ducts; so, somites. The experiment was repeated in triplicate, with eight embryos representative of the group imaged. Scale bar in A,A′, 250 μm. Scale bar in G,I, 50 μm

Expression Data

Gene:	ndrg1a
Fish:	AB
Condition:	oxygen content
Anatomical Terms:	aortic arch caudal artery caudal vein plexus dorsal aorta epiphysis hatching gland inner ear ionocyte lateral line primordium mid cerebral vein primordial midbrain channel pronephric duct somite
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	oxygen content
Observed In:	aortic arch caudal artery caudal vein plexus dorsal aorta hatching gland inner ear lateral line primordium mid cerebral vein primordial midbrain channel somite
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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