FIGURE
Fig. 2
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- ZDB-FIG-221121-2
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- Hudson et al., 2021 - A complete Protocadherin-19 ectodomain model for evaluating epilepsy-causing mutations and potential protein interaction sites
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Fig. 2
Figure 2. The composite structure of Pcdh19 with its complete extracellular domain Our structural model of Pcdh19 is shown mediating adhesion between two adjacent cells. Extracellular domains are shown in surface representation from the composite structure (Data S1), which is based on dr Pcdh19 EC1-4 (PDB: 5IU9) and dr Pcdh19 EC3-6 (PDB: 6PGW). The transmembrane segment is represented by a helical coil and the intrinsically disordered intracellular segment is shown fading out of view. See also Figure S6 and the STAR Methods. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Structure (London, England : 1993), 29(10), Hudson, J.D., Tamilselvan, E., Sotomayor, M., Cooper, S.R., A complete Protocadherin-19 ectodomain model for evaluating epilepsy-causing mutations and potential protein interaction sites, 1128-1143.e4, Copyright (2021) with permission from Elsevier. Full text @ Structure