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ID

ZDB-FIG-220914-52

Publication

Hu et al., 2022 - Iron supplementation inhibits hypoxia-induced mitochondrial damage and protects zebrafish liver cells from death

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FIGURE 2

Iron supplementation could improve the survival activity of ZFL cells under hypoxia stress, but iron chelation and inhibition of ferroptosis could not. (A–C) Survival rate of ZFL cells analyzed with PrestoBlue™ HS Cell Viability Regent after treated with a series of concentrations of FAC (A), DFO (B) and Fer-1 (C) under hypoxic stress from one to 4 days. Hypoxia 0 mM or hypoxia 0 µM was used as a control group for significance analysis. (D) The microscope analysis of morphology changes of ZFL cells under normoxia or treated with FAC (2.5 mM), DFO (10 µM) and Fer-1 (2.5 µM) under hypoxic stress for 3 days. Error bars, mean ± s.d., n = 3 (biological replicates).

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Physiol.