FIGURE

Fig. 2

ID
ZDB-FIG-220912-121
Publication
Born et al., 2022 - eif4ebp3l-A New Affector of Zebrafish Angiogenesis and Heart Regeneration?
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Fig. 2

At day three after cryoinjury eif4ebp3l is downregulated in the injured area (IA). (A,B) Images of RNAscope in situ hybridizations (ISH) for eif4ebp3l (left panels, orange in the right panel) and eGFP (middle panels, green in the left panel) on cryosections of Tg(fli1:eGFP) zebrafish heart three days post cryoinjury (dpci). (A) Overview of the whole zebrafish heart; the IA is outlined with the dotted box. Eif4ebp3l was highly expressed in the healthy myocardium and downregulated in the IA. (B) Higher magnifications of the IA. eGFP was highly expressed in the border zone, where the formation of new endothelial vessels originated. Eif4ebp3l was co-located to these eGFP-positive endothelial cells in the border zone (white arrows), whereas in the center of the injured area its mRNA expression was strongly downregulated. Scale bar = 100 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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