FIGURE
Fig. 10
- ID
- ZDB-FIG-220912-101
- Publication
- Atienzar-Aroca et al., 2022 - Transgenic Overexpression of Myocilin Leads to Variable Ocular Anterior Segment and Retinal Alterations Associated with Extracellular Matrix Abnormalities in Adult Zebrafish
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Fig. 10
Figure 10. Top-50 DEGs in altered eyes of old (two-year-old) male myoc transgenic zebrafish. (A) Down- and (B) up-regulated genes identified by high-throughput RNA sequencing with significant differences coinciding in the comparison with the two wild-type ocular transcriptomes (Tg/+ OA vs. +/+1 and Tg/+ OA vs. +/+2). Confirmation by qRT-PCR of differential gene expression of selected (C) down- and (D) up-regulated genes. Aliquots of RNA preparations used for transcriptomic analyses were used as templates in qRT-PCR. Values represent the average of six experimental replicas. **: p < 0.01; ***: p < 0.001, Student’s t-test.
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Expression Data
| Genes: | |
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| Fish: | |
| Anatomical Term: | |
| Stage: | Adult |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
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| Observed In: | |
| Stage: | Adult |
Phenotype Detail
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Full text @ Int. J. Mol. Sci.