Gene
lgsn
- ID
- ZDB-GENE-060312-26
- Name
- lengsin, lens protein with glutamine synthetase domain
- Symbol
- lgsn Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have glutamate-ammonia ligase activity. Involved in cell differentiation and lens morphogenesis in camera-type eye. Localizes to actin filament. Is expressed in lens. Orthologous to human LGSN (lengsin, lens protein with glutamine synthetase domain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Harding et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR008146 | Glutamine synthetase, catalytic domain |
| Domain | IPR008147 | Glutamine synthetase, N-terminal domain |
| Homologous_superfamily | IPR014746 | Glutamine synthetase/guanido kinase, catalytic domain |
| Homologous_superfamily | IPR036651 | Glutamine synthetase, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Glutamine synthetase, catalytic domain | Glutamine synthetase/guanido kinase, catalytic domain | Glutamine synthetase, N-terminal domain | Glutamine synthetase, N-terminal domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q29RF4
|
668 |
Interactions and Pathways
No data available
Plasmids
No data available