FIGURE

Fig. 4

ID
ZDB-FIG-220627-15
Publication
Lee et al., 2022 - FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease
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Fig. 4

Fmnl2 knock-down reduces the number of activated microglia and alters the amyloid load. af dIHCs for L-plastin (microglia) and kdrl:GFP with DAPI counterstain on control morpholino (a, b), Aβ42+ control morpholino (c, d), and Aβ42+ fmnl2a/b morpholino (e, f) injected brains. a′, b′, c′ L-plastin channel alone. g Quantification graph for the number of activated microglia in the indicated conditions. h High magnification images from three blood vessels in Aβ42+ control morpholino-injected zebrafish brains (left column) and Aβ42+ fmnl2a/b morpholino-injected brains (right column). Scale bars as indicated

Expression Data
Gene:
Antibody:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage: Adult

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Adult

Phenotype Detail
Acknowledgments
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