FIGURE

Fig. 2

ID

ZDB-FIG-220617-6

Publication

Lai et al., 2022 - DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells

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Fig. 2

Yap1 and Wwtr1 are localized in epidermal basal cells (EBCs) and EVL cells.

(A) Maximum intensity projections of the epidermis on the lateral yolk stained with P63, and Wwtr1 or Yap1 antibodies at indicated developmental stages. Insets, demarcated in red, show overlay of P63 and Yap1/Wwtr1. Arrowheads – P63-positive basal cells; arrows – peridermal cells; triangles – peridermal cell junctions. Scale bars, 10 µm. (B) Boxplots of normalized intensities of Yap1 and Wwtr1 in the nucleus of P63-positive and P63-negative cells in the basal epidermis. t-Tests were carried out to compare these intensities between the two groups. ***p<0.001.

Expression Data

Genes:	wwtr1 yap1
Antibodies:	Ab1-tp63 Ab1-wwtr1 Ab1-yap1
Fish:	WT
Anatomical Terms:	integument integument nucleus periderm peridermal cell cell-cell junction peridermal cell nucleus
Stage Range:	Bud to 20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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