FIGURE

Figure 3.

ID

ZDB-FIG-220430-17

Publication

Xue et al., 2022 - Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation

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Figure 3.

Elimination of ROS accumulation rescued the disrupted blood vessel. (a) The NRF2 mRNA expression level was examined in HUVECs exposed to different CSE concentrations with or without NAC (1 mM) for 24 h. (b) Representative images indicated NRF2 nuclear localization from different treated groups. (c) Pearson correlation coefficient for the co-localization of NRF2 and DAPI. (d) Representative images for the flk::GFP zebrafish with or without NAC (5 mM) under different concentrations of CSE. (e) Blood vessel lengths were quantified for different treatments (n = 16). Data presented are the mean ± s.e.m. Unpaired Student's t-test, ^#p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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