FIGURE

FIGURE 7

ID

ZDB-FIG-220406-18

Publication

Zhou et al., 2022 - Dopamine Homeostasis Imbalance and Dopamine Receptors-Mediated AC/cAMP/PKA Pathway Activation are Involved in Aconitine-Induced Neurological Impairment in Zebrafish and SH-SY5Y Cells

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FIGURE 7

Effects of SCH23390, sumanirole and H-89 on intracellular Ca²⁺ changes induced by aconitine in zebrafish larvaes. (A) Effects of SCH23390 on intracellular Ca²⁺ changes induced by aconitine. (B) Sumanirole suppressed aconitine-induced the increase of intracellular Ca²⁺. (C) Pretreatment with SCH23390 and sumanirole inhibited the rise of intracellular Ca²⁺ aconitine-stimulated. (D) H-89 inhibited the increase of intracellular Ca²⁺ induced by aconitine. All photographs were taken under a confocal microscope (100×). The values are expressed as mean ± SD, n = 8. *p < 0.05, **p < 0.01, ***p < 0.001 vs. control groups. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 vs. aconitine-treated groups.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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