FIGURE

FIGURE 2

ID

ZDB-FIG-220406-13

Publication

Zhou et al., 2022 - Dopamine Homeostasis Imbalance and Dopamine Receptors-Mediated AC/cAMP/PKA Pathway Activation are Involved in Aconitine-Induced Neurological Impairment in Zebrafish and SH-SY5Y Cells

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FIGURE 2

Cell damage of zebrafish larvaes and SH-SY5Y cells caused by aconitine. (A) The images of aconitine-treated larvaes by DCFH-DA (100×), n = 6. (B) The images of aconitine-exposed larvaes by TUNEL assay (100×), n = 3. (C) Cell viability of SH-SY5Y cells after 24 h or 48 h aconitine exposure, n = 8. (D) The images of aconitine-treated SH-SY5Y cells by DCFH-DA (200×), n = 3. (E) SH-SY5Y cell apoptosis aconitine-induced based on Annexin V/PI double staining by flow cytometry, n = 3. All photographs were taken under a stereoscopic fluorescence microscope or confocal microscope. The values are expressed as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001 vs. control groups.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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