FIGURE

Figure 2.

ID

ZDB-FIG-220404-15

Publication

Pinion et al., 2022 - Differential electrographic signatures generated by mechanistically-diverse seizurogenic compounds in the larval zebrafish brain

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Figure 2.

Example data obtained from in vivo electrophysiological recording in a 4-dpf elavl3:GCaMP6s zebrafish larva exposed to 62.5 μM donepezil. A, A representative frequency binned wavelet transformation from a single larva, the top graph shows the baseline and the bottom wavelet transform after drug administration. These transformations were used to identify events from the full timeseries. B, A plot of the Euclidean distance of each time point from the average of the baseline. The black dotted line represents the threshold for selecting events. All peaks above this line were selected and used to find events which were subsequently clustered.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	jf4Tg/jf4Tg
Condition:	chemical treatment by environment: donepezil
Observed In:	midbrain modulation of chemical synaptic transmission
Stage:	Day 4

Phenotype Detail

Acknowledgments

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