FIGURE

Figure 7

ID

ZDB-FIG-220403-42

Publication

Laghi et al., 2022 - Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder

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Figure 7

Viral infection in IFN-defective larvae. (A) IFN-receptor (crfb1 and crfb2 genes) or control morphants infected at 3 dpf in the coelomic cavity; qRT-PCR. (B, C) Offspring from an incross of heterozygous triple IFN-mutants. (B) Larvae injected with SINV-GFP IV at 3 dpf, analyzed by fluorescence imaging at 48 hpi. (C) Larvae injected with SARS-CoV-2, either at 3 dpf in the coelom or at 4 dpf in the swim bladder; analyzed by qRT-PCR at 0 or 48 hpi. Statistical analysis by ordinary 1-way ANOVA in (B), by Kruskal–Wallis test in (C). ns, not significant; ****p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Infect Microbiol