FIGURE

Figure 6

ID

ZDB-FIG-220402-42

Publication

Jadhao et al., 2022 - Endoglin Modulates TGFβR2 Induced VEGF and Proinflammatory Cytokine Axis Mediated Angiogenesis in Prolonged DEHP-Exposed Breast Cancer Cells

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Figure 6

Representative and quantitative results of endoglin-mediated MAPK/p38 signaling and cytokine regulation. (A) Western blotting results showing upregulation of MAPK, phospho-MAPK, p38, and phospho-p38 in DEHP-treated MDA-MB-231 cells, and endoglin reversed protein expression. (B) Representative results of the antibody angiogenesis array showing endoglin-mediated expression of the inflammatory cytokines GMCSF and VEGF. (C–H) Quantification of the expression of IL1α, IL1β, IL6, IL8, GMCSF, and VEGF in control and DEHP-exposed MDA-MB-231 cells (mock- and shENG-treated). +ve ctrl: positive control; ** p < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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