Figure 10.

Kilroy et al., 2022 - Beneficial impacts of neuromuscular electrical stimulation on muscle structure and function in the zebrafish model of Duchenne muscular dystrophy
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Figure 10.


Endurance neuromuscular electrical stimulation (eNMES) positively benefits neuromuscular health, function, and survival in dmd mutants. Muscle fibers in dmd mutants treated with eNMES are more organized and have fewer detachments. Neuromuscular junctions (NMJs) are longer in eNMES-treated dmd mutants. Sarcomeres are longer and nuclei are more ellipsoid and aligned. eNMES-treated mutants swim faster and more distance than control siblings. Both heme oxygenase and Itga7 are required for eNMES-mediated improvements.

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