FIGURE

FIGURE 1

ID

ZDB-FIG-220325-9

Publication

Van Gils et al., 2022 - The Abcc6a Knockout Zebrafish Model as a Novel Tool for Drug Screening for Pseudoxanthoma Elasticum

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FIGURE 1

Light microscopy examples of ARS-stained abcc6a^cmg52/cmg52 specimens. Examples of 10 dpf untreated (A,C,E,G,I) and treated (B,D,F,H,J) abcc6a^cmg52/cmg52 animals. Compounds per set are (A,B) 80 µM vitamin K1, (C,D) 20 µM sodium thiosulfate (E,F) 100 µM etidronate, (G,H) 100 µM alendronate and (I,J) 10 mM magnesium citrate.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	abcc6a^cmg52/cmg52 (AB)
Conditions:	chemical treatment by environment: alendronate sodium trihydrate chemical treatment by environment: etidronate disodium chemical treatment by environment: magnesium citrate chemical treatment by environment: sodium thiosulfate chemical treatment by environment: phylloquinone
Observed In:	notochord outer sheath cell biomineral tissue development
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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