FIGURE

FIGURE 3

ID

ZDB-FIG-220325-11

Publication

Van Gils et al., 2022 - The Abcc6a Knockout Zebrafish Model as a Novel Tool for Drug Screening for Pseudoxanthoma Elasticum

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FIGURE 3

Example of ectopic speckling following 35 µM STS-treatment. Snapshot group images of (A) control and (B) 35 µM STS-treated larvae at 10 dpf with unknown genotypes. 35µM sodium thiosulfate abolished spinal mineralization and concomitantly ventral mineralized nodules were identified (arrowheads) in all treated animals. Opacity of the specimens prevented identification of the anatomical sites of the nodules.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	abcc6a^cmg52/cmg52 (AB)
Condition:	chemical treatment by environment: sodium thiosulfate
Observed In:	notochord outer sheath cell biomineral tissue development whole organism biomineral tissue development
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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