FIGURE

Figure 5

ID
ZDB-FIG-220131-328
Publication
Cheng et al., 2022 - Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis
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Figure 5

RNA sequencing results reveal differentially expressed genes (DEGs) and enriched KEGG pathways in A549/DDP cells treated with or without OP-B. A. Volcano plot (bottom) showing 690 decreased genes and 1149 upregulated genes. B. Venn diagram showing DEGs between A549/DDP cells treated with or without OP-B. C. Top enriched KEGG pathways for these 652 DEGs, including pyroptosis signaling. D. Transcriptiomic RNA-seq identified 1839 DEGs. Hierarchical cluster analysis (top) of significantly differentially expressed mRNAs between A549/DDP cells treated with or without OP-B.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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