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ZDB-FIG-211029-1

Publication

O'Meara et al., 2021 - Genetic landscape of T cells identifies synthetic lethality for T-ALL

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Fig. 1

a Identification of genetic variants perturbing T cell development through large-scale forward genetic screens in zebrafish larvae. b Delineation of the genetic network underlying the development of T cells by pairwise interaction analyses. c Phenocopy of a subset of genetic interactions using small molecule inhibitors. d Tumour treatment in an in vivo model of T-ALL based on the information obtained on synthetic lethal interactions.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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