FIGURE

Figure 8

ID

ZDB-FIG-211002-9

Publication

Chebli et al., 2021 - The localization of amyloid precursor protein to ependymal cilia in vertebrates and its role in ciliogenesis and brain development in zebrafish

Other Figures

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Figure 8

Structural integrity of ependymal cilia in WT and appa^−/−appb^−/− zebrafish. Transmission electron microscopy of adult zebrafish ependymal cilia of WT (A–D) and appa^−/−appb^−/− mutant (E–H) adult zebrafish. (A,E) Overview of ependymal cilia of the central canal. (B,F) Longitudinal view on the axoneme of the cilia composing its core, the transition zone including the ciliary pit between the cilia core and the cellular membrane and the basal body containing the cilia centrioles, highlighted with increased signal. In (C,G), cross-sections of cilia. (D–H) Zoom on cross-section of individual cilia showing (9 + 2) microtubule doublet organization. Scale bar: (A,E) = 1 µm, (B,C,F,G) = 200 nm, (D,H) = 50 nm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	appa^{zf3579/zf3579}; appb^{zf3355/zf3355} (AB)
Observed In:	ependymal cell 9+2 motile cilium
Stage:	Adult

Phenotype Detail

Acknowledgments

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