FIGURE

Figure 6

ID

ZDB-FIG-211002-102

Publication

Liao et al., 2021 - Establishment of a Drug Screening Model for Cardiac Complications of Acute Renal Failure

Other Figures

All Figure Page

Back to All Figure Page

Figure 6

Evaluation of the effect of digoxin and enalapril on the CRS-3 model. (A) Heart images of zebrafish larvae (Control, zebrafish larvae treated with MTZ, zebrafish larvae treated with digoxin or enalapril) (n = 5) at 2 dpi are shown. Scale bar: 100 ?m. (B,C) Heart rate was detected by the dynamic change pattern in the ventricle of zebrafish larvae. (D) ARF-induced heart enlargement can be decreased by digoxin and enalapril (n = 5). (E) Compared with the control group, treatment of ARF larvae with digoxin and enalapril resulted in significant increases in blood flow velocity (n = 5). (F) After treatment with digoxin or enalapril, the survival rate of ARF zebrafish larvae was increased (n = 60). Mean � SEM; ns, not significant; * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001, ANOVA/Dunnett?s test compared with untreated ARF zebrafish larvae.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomolecules