FIGURE

Figure 5

ID

ZDB-FIG-211002-101

Publication

Liao et al., 2021 - Establishment of a Drug Screening Model for Cardiac Complications of Acute Renal Failure

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Figure 5

Changes of blood flow and blood vessels in ARF larvae. (A) The erythrocytes in the caudal artery (CA) (green arrow), caudal vein (CV) (white arrow), posterior cardinal vein (PCV) (green arrow) and dorsal aorta (DA) (white arrow) of Tg(cdh17:Dendra2-NTR; flk1:GFP;gata1:DsRed) zebrafish larvae treated with MTZ or control are shown. Scale bar: 200 ?m. (B) After treatment with MTZ, the caudal artery blood flow velocity of zebrafish larvae (n = 5) was evaluated using ImageJ. (C?E) Confocal images of blood vessels around the heart and tail of Tg(cdh17:Dendra2-NTR; flk1:GFP;gata1:DsRed) zebrafish larvae treated with MTZ or control (n = 5). The Scale bars of (C) and (D,E) are 100 ?m and 200 ?m, respectively. The red and white line segments represent the vessel lumen of zebrafish larvae. CA, caudal artery; CV, caudal vein. Mean � SEM; * p < 0.05 and **** p < 0.001, ANOVA/Dunnett?s test compared with control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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