FIGURE

Figure 4

ID

ZDB-FIG-211001-4

Publication

Morris et al., 2021 - Glucose inhibits haemostasis and accelerates diet-induced hyperlipidaemia in zebrafish larvae

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Figure 4

Glucose-injected larvae have increased lipid accumulation following a high fat diet. (A) Schematic of the high fat feeding challenge assay to measure lipid accumulation in glucose-injected larvae. (B) Bright field images of 6 dpf Oil Red O-stained larvae, demonstrating darker vascular staining in glucose-injected larvae. Box indicates location of inset, arrowheads indicate stained intersegmental vessels in inset, asterisk indicates intestinal lumen which was excluded from analysis. (C) Quantification of lipid accumulation in 5 dpf glucose-injected larvae. (D) Quantification of lipid accumulation in 6 dpf glucose-injected larvae challenged with a high fat diet from 5 dpf. (E) Quantification of lipid accumulation in 7 dpf glucose-injected larvae challenged with a high fat diet from 5 dpf. Statistical testing by t test. Data are representative of 2 biological replicates.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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